White Blood Cell
White blood cells or leukocytes (leucocytes), are cells of the immune system involved in defending the body against both infections, diseases and foreign materials. Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a haematopoietic stem cell (Brooks, 2008). They live for about three to four days in the average human body.
Leukocytes are found throughout the body, including the blood and lymphatic system (Maton et al., 2002).
Types of White Blood Cell
There are several different types of WBCs, they all have many things in common, but are all distinct in form and functions. A major distinguishing feature of some leukocytes is the presence of the granules, white blood cells are often characterized by granulocytes and agranulocytes.
- Granulocytes (polymorphonuclear leucocytes): leukocytes characterized by the presence of different staining granules in their cytoplasm when viewed under light microscopy. These granules are membrane bound enzymes that act primarily in the digestion of endocytosed particles. There are three types of granulocytes: which are named according to their staining properties.
- Neutrophils:- Its main function is defence against bacteria
- Easipophils:- Kills parasites and have a role in allergic
- Basophil:- Not well understood but they function in allergic reaction
- Agranulocytes (Mononuclear leukocytes): Leukocytes characterized by the absence granules in their cytoplasm. Although the names implies a lack of granules these cells do contain non-specific azurophilic granules which are lysosomes (Gartner et al., 2007). The cell include;
- Lymphocytes:- They are the killer cells (B cells and T cells)
- Monocytes:- They enter the tissue, where they become larger and turn into macrophages.
But the neutrophil is the subject of interest in this experimental study.